The Value Express Scripts Delivers
A prescription drug doesn’t work if it’s priced out of reach. Express Scripts fights to ensure clients and consumers have access to safe, effective and affordable medications and life-sustaining or life-saving therapies.
Who We Are
18k employees across 20 sites in the U.S.
3,500+ patient service advocates
Thousands of pharmacists, doctors and nurses with specialties by disease state
Working on Client Terms & Defending Consumer Wallets
Express Scripts offers clients multiple options to support the unique needs of their populations. Clients have complete control and flexibility to choose their specific benefit design, network and pricing structure. Employers, health plans, labor unions, government organizations and many others partner with us because of the significant value we create by:
- Negotiating rebates and discounts from drug manufacturers and providing formulary management services
- Negotiating reimbursement rates and reduced fees with thousands of retail pharmacies nationwide to create industry-leading pharmacy networks
- Encouraging the use of generics, biosimilars and more affordable brand-name drugs
- Managing high-cost specialty medications with high-touch clinical care coordination
- Improving population health, reducing waste and increasing clinically appropriate medication adherence
Clients can use the savings we generate to reduce plan costs and insurance premiums, fund wellness programs, and deliver other benefits to their covered employees and dependents.
If we didn’t provide significant value for our thousands of partners, we wouldn’t exist.
Who We Serve
1 in 3 Americans
~2,300 commercial employers
40+ health plans & government employers
42 Medicare Advantage plans
15 Medicaid plans in 13 states
24 PBMs & wholesale market participants
Industry-leading and first-to-market innovations that matter
Patient Assurance Program
First in the industry to cap the cost of insulin at $25 for 30-day supplies
Copay Assurance Plan
$5 for generics & specialty generics, $25 for preferred brand drugs, $45 for preferred specialty brands under a client’s prescription drug benefit
ClearCareRx
Fully transparent client pricing model with 100% rebate and spread pass through – proven to drive lower drug trend & total medical costs
IndependentRx
Expands rural health access via independent pharmacies – offering greater reimbursements and care services, while enhancing support with industry-first Independent Pharmacy Advisory Committee
Health Connect360
Performance-based clinical solution driving $399 PMPY1 and gaps-in-care closures 14x faster2
Embarc Benefit Protection
Makes multi-million dollar gene therapies more affordable with $0.99 PMPM flat fee and $0 out-of-pocket cost
SafeGuardRx
Value-based program that saved clients $6.4B3 in 2022 through lower medical & drug costs
Driving better clinical outcomes for those we serve

Preventing thousands of incidents of stroke, heart failure and other serious health issues per year through our clinical programs

Driving >80% adherence rates4 across the majority of specialty therapeutic resource centers

Developing >2.4M safety interventions5, preventing adverse events and hospitalizations for patients each year
Express Scripts, a key part of The Cigna Group, provides critical value-added health services to meet the evolving needs of stakeholders across the U.S.
1 Evernorth Health Connect360, “Making connections that count”
3 SafeGuardRx | Home (Evernorth Data)
4 Accredo Specialty data, Book of Business Average 2021
5 RationalMed data, 2020 Express Scripts book-of-business